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Melanopsin And Sleep Modulation: A Bright Future For Light Therapy?
Light strongly influences human physiology and notably sleep regulation. An international team of scientists, including Patrice Bourgin from CNRS "Institut des neurosciences cellulaires et intçİgratives" in Strasbourg, has just published a detailed study in PlosBiology on the role of melanopsin, a molecule involved in mediating the effects of light on sleep. These scientists also revealed evidence of new interactions between the different mechanisms acting on the duration and quality of sleep and alertness.
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GlaxoSmithKline And Genmab Announce Top-line Results For Ofatumumab In Rheumatoid Arthritis
GlaxoSmithKline (GSK) and Genmab A/S (OMX: GEN) announced preliminary top-line results from a Phase III study of ofatumumab administered intravenously for the treatment of rheumatoid arthritis (RA) in patients who had an inadequate response to methotrexate. The study met the primary endpoint, ACR20 at 24 weeks, which indicates a 20 percent or greater improvement in the number of swollen and tender joints, as well as improvements in other disease-activity measures.
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International Team Tracks Clues To HIV
Rice University"s Andrew Barron and his group, working with labs in Italy, Germany and Greece, have identified specific molecules that could block the means by which the deadly virus spreads by taking away its ability to bind with other proteins.
Endocrinology

Child Safeguarding One Of The Most Important Priorities For The NHS

Commenting on the report, she said: "Despite the progress many NHS organisations have made, and the commitment of individuals working in the health service, there is clearly much more that can be done to make sure children are protected properly. "Central to the improvement of child safeguarding is the creation of a culture that empowers staff to put the safety of children at the heart of what they do. "Leadership is the starting point in culture change and all boards of NHS trusts should ensure that best practice and the necessary frameworks for child safeguarding are followed. This means promoting a culture of questioning amongst staff and learning the lessons from both this report and other organisations" safeguarding arrangements. "It is absolutely vital that NHS trust boards are connected to what is going on in all parts of their organisations. Giving adequate time to specialist professionals working in safeguarding services and having the correct and up-to-date training systems in place for all staff are essential to ensure health workers are able to make the right call on incredibly tough and important decisions. "As part of this, we also agree with this report"s recommendation to ensure all GPs have the necessary skills and training. PCTs, in particular, have a role in working with local practices to ensure the provision of the best level of child protection services, at that vital point of contact for families with the NHS and other children"s services." The NHS Confederation


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