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Erectile Dysfunction Might Be Associated With Chronic Periodontal Disease: Two Ends Of The Cardiovascular Spectrum
UroToday.com - Together with Drs. Heruti, Bechor, Justo and Galor, we studied 815 Israeli male adults of whom 305 had complete data and were included in the statistical analysis. In the analyzed population, 2.1% of people without erectile dysfunction (ED) had advanced periodontal disease (defined as recession of periodontal bone of 6 mm or more) in comparison to 9.8% of the mild ED and 15.8% of the moderate/severe ED populations, respectively. However, due to the relatively small groups, we could not present the odds ratio. We are now planning a large-scale study to further establish the association between the two conditions.
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Obama Prepares For Tonight's Primetime Address As He Pushes Reform
President Barack Obama prepares his primetime address for tonight as he ups the ante for reform. This week alone, Obama has visited two hospitals, made a trip to Cleveland for a town-hall meeting and conducted a conference call urging bloggers to motivate their followers. Such efforts come amid increasing difficulties and roadblocks set by the GOP as health care bills stall in Congress.
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Biothera Launches Clinical Trial In KRAS-Mutated Colorectal Cancer Patients
Biothera has initiated a Phase II clinical trial in stage IV KRAS-mutated colorectal cancer patients with its investigational drug Imprime PGG® in combination with Erbitux® (cetuximab), the company announced today.
Sexual Health

Diet To Reduce Mild Hyperoxaluria In Patients With Idiopathic Calcium Oxalate Stone Formation: A Pilot Study

UroToday.com - You pass what you eat! If you eat wisely, passage shouldn"t be painful. This may be especially true for stone formers. To be sure, high fluid intake resulting in a urine output of > 2 liters per day is key; however, what is eaten also plays a role. In this study among 56 hyperoxaluric patients on a low oxalate diet, the institution of a low salt (4-5 grams/day), low animal protein (approximately 20 grams per day vs. a norm of 50 grams per day), and normal calcium diet over a 3 month period, resulted in a statistically significant drop in 24 hour urine calcium (364 to 263 mg/d) and oxalate (50 to 35 mg/d). Sodium also dropped (238 to 118 mmol/d) and the patients had a 2 kilogram fall in body weight; both of these changes were likewise statistically significant. None of these changes occurred in a group of patients just instructed on a low oxalate diet. Hypothetical explanations for the beneficial effects include: low oxalate intake, less oxalate intestinal absorption (e.g. less fat in the diet leaves more calcium to bind oxalate in the gut), and theoretically less endogenous oxalate production (e.g. due to lower intake of certain amino acids and carbohydrates). Unfortunately, supersaturation data for calcium oxalate was not supplied; likewise, there is no long term follow-up to show that these presumed beneficial effects translated into fewer future stone episodes for these patients. These data will be necessary before this diet can be widely adopted, but in the mean time, it seems like a relatively simple and palatable way to go. Nouvenne A, Meschi T, Guerra A, Allegri F, Prati B, Fiaccadori E, Maggiore U, Borghi L Urology. 2009 Apr;73(4):725-30, 730.e1. doi: 10.1016/j.urology.2008.11.006 Reported by UroToday.com Medical Editor Ralph V. Clayman, MD UroToday - the only urology website with original content written by global urology key opinion leaders actively engaged in clinical practice. To access the latest urology news releases from UroToday, go to: www.urotoday.com Copyright © 2009 - UroToday


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