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Teeth Whitening

Gpx5: Sperm Shouldn't Leave The Testes Without This Protein
Joel Drevet and colleagues, at Clermont Universitç©, France, have identified a protein that helps protect immature mouse sperm after they have been released into a region of the testis known as the epididymis, which is where they undergo maturation. Although male mice lacking this protein, Gpx5, had normal looking sperm and were equally as efficient as normal male mice at fertilizing female mice, an increased incidence of miscarriages and fetal developmental defects were observed when normal female mice were mated with Gpx5-deficient males over 1 year old compared with normal male mice of the same age. Further analysis indicated that Gpx5 acts as an antioxidant in the epididymis, protecting the sperm from oxidative stress. As discussed by the authors, and, in an accompanying commentary, John Aitken, at the University of Newcastle, Australia, these data have immense clinical relevance as age-related DNA damage to human sperm has been associated with a range of adverse outcomes including decreased fertility, and increased rates of miscarriage and childhood disease.
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University Of Pittsburgh Cancer Institute Researcher Dr. Merrill Egorin Honored With ASCO Translational Research Professorship
Merrill Egorin, M.D., professor of medicine and pharmacology at the University of Pittsburgh Cancer Institute (UPCI), has received the 2009 American Society of Clinical Oncology (ASCO) Translational Research Professorship for his work in improving cancer treatments and supporting the next generation of researchers.
News of the day
Shedding Light On Social Brain Development
The capacity to figure out what others are thinking and what they mean is an ability unique to people that"s central to our lives. A new study on the neural mechanisms that govern these abilities sheds light on the relation between how people and groups interact, on the one hand, and how the brain develops and functions, on the other.
Mental Health

Fatherhood Influences Men In Mental Health Decisions

Being a father is an important factor in a man"s decision to seek help for mental health issues, according to a survey released by the American Psychiatric Association. More than 6 million men suffer from depression each year, and though many try to deal with it on their own, the survey indicates that fathers are more likely to take their mental health seriously for the sake of their children. Over 90 percent of men surveyed said their role as a father or legal guardian would have an impact on their decision to seek help if they were feeling depressed. "It is encouraging to see that fathers are open to getting help and that some of the stigma surrounding men and depression is waning," stated Jeffrey Borenstein, M.D., Chair of the Council on Communications at the American Psychiatric Association. "A father who takes care of himself is taking care of his whole family." Survey respondents were more likely to say they would encourage their fathers to seek help for depression if they are parents themselves. More than 90 percent of parents or guardians who still have contact with their fathers said they would be likely to encourage their own fathers to seek help for depression if they felt it was interfering with his work or relationships, while only 85 percent of the nonparents would encourage their father to get help. While stigma surrounding mental health issues has declined, many men indicated that they are more comfortable discussing other health issues. Half of the men surveyed said it would be easier or equally easy to talk to their fathers about depression, while a third said it would be easier to talk to them about screening for cancer than seeking help for depression. The national online survey was conducted within the United States by Harris Interactive on behalf of The American Psychiatric Association between June 12-16, 2009 among 2,274 adults age 18+, 1040 of whom were male; 235 of those males were fathers or legal guardians. No estimates of theoretical sampling error can be calculated; a full methodology is available. American Psychiatric Association


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