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Aspirin As A Prophylaxis For Fatal Pulmonary Embolism
A study published provides results which challenge the current NICE guidelines (set in April 2007) relating to the use of low-molecular weight heparin (LMWH) rather than aspirin as a thromboprophylaxis following orthopaedic surgery.
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Three Rivers Announces Positive Results From Phase 3 DIRECT Trial Of Once-Daily INFERGEN(R) With Ribavirin In Hepatitis C Virus Treatment Failures
Three Rivers Pharmaceuticals announced positive results of the U.S.-based, randomized Daily-Dose Consensus Interferon and Ribavirin: Efficacy of Combined Therapy (DIRECT) clinical trial authored by Bruce R. Bacon, M.D., of Saint Louis University, and colleagues at 44 centers in the United States. The primary endpoint of increased sustained virological response (SVR), was achieved demonstrating that INFERGEN provides a second chance to those HCV patients failing to respond to standard, first-line therapy of pegylated interferon (PEG-IFN) plus ribavirin (RBV). "The retreatment of PEG-IFN/RBV nonresponders with INFERGEN and RBV is safe and efficacious and can be considered a retreatment strategy for patients failing previous therapy with PEG-IFN/RBV, especially in interferon-sensitive patients with lower baseline fibrosis scores," stated Dr. Bruce Bacon the lead Investigator for the study.
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Medical Defence Union Cautions Members About Assisted Suicide Discussions, UK
Doctors are being reminded that assisting a suicide is illegal in England and Wales and that they should not give advice to patients to help them travel abroad to take their own lives.
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Prostate Cancer Screening And Trust Of Physician Evaluated

Trusted health care s and continuity of care may help reduce the risk of prostate cancer deaths in African-American men, according to a study published in the current issue of the journal Cancer. James Mohler, MD, Chair of the Department of Urology at Roswell Park Cancer Institute (RPCI), and William R. Carpenter, PhD, Department of Health Policy and Management at the University of North Carolina, are lead investigators. The research analyzed physician trust, continuity of health care, the regular of health care and their effects on prostate cancer early detection among newly-diagnosed prostate cancer patients from North Carolina and Louisiana. The study enrolled 1,031 African-American and Caucasian-American men, age 50 and over, within weeks of their diagnosis of prostate cancer. A study nurse conducted a structured survey and acquired biological specimens in a home visit and abstracted medical information directly from medical records. In this study, the stage of prostate cancer at diagnosis was similar between races, but the mean Gleason scores, an indication of the aggressiveness of the disease, were higher for African-Americans than Caucasian-Americans. African-Americans were less likely than Caucasians to report participation in prostate cancer screening prior to diagnosis. Men without a prior history of screening were more likely to be diagnosed with advanced disease and/or more aggressive forms of prostate cancer. However, when men of either race had established relationships with the same health care provider, these differences in prostate cancer aggressiveness went away. Therefore, addressing racial differences in use of screening may reduce racial disparities in prostate cancer diagnosis and treatment, and, by extension, may reduce disparities in prostate cancer deaths. "The goal of the study was to gain a deeper understanding of the role of racial disparities in prostate cancer outcomes," said Dr. Mohler. "These findings suggest that differences in screening result from inconsistent or poorer quality interaction between an African-American man and the American health care system. If the interaction is poor, the care giver may not get around to discussing or offering preventive health care, such as prostate cancer screening. Improving the interaction between all men, and especially African-American men, and their primary care givers should reduce prostate cancer deaths in all men and decrease the racial disparity in prostate deaths in African-American men." Dr. Carpenter added, "Factors in health care systems, including setting and continuity of care, may hinder the development of physician-patient relationships. These factors may preclude or limit discussions about preventive health care and early detection of disease through prostate cancer screening." The mission of Roswell Park Cancer Institute (RPCI) is to understand, prevent and cure cancer. RPCI, founded in 1898, was one of the first cancer centers in the country to be named a National Cancer Institute-designated comprehensive cancer center and remains the only facility with this designation in Upstate New York. The Institute is a member of the prestigious National Comprehensive Cancer Network, an alliance of the nation"s leading cancer centers; maintains affiliate sites; and is a partner in national and international collaborative programs. Roswell Park Cancer Institute


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