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CDC, National Chlamydia Coalition Partner To Raise Awareness, Testing Rates
The National Chlamydia Coalition is partnering with the Centers for Disease Control and Prevention to increase public awareness and screening efforts for chlamydia, the most common sexually transmitted infection in the U.S., the Wall Street Journal reports. According to CDC, there were 1.1 million recorded cases of chlamydia in 2007, although experts estimate that there are twice as many cases that are not detected largely because the infection often causes few symptoms and many people go unscreened. The infection is three times more common in women than men, which experts say could be because men eliminate it from their bodies more readily than women. Chlamydia is treatable with a single dose of antibiotics, but if left untreated, it can lead to infertility or increased risk for ectopic pregnancies in women.CDC recommends that all sexually active women younger than age 26 be tested annually for the infection, as well as older women who have had a change of sexual partners. However, fewer than 40% of women in those groups are tested, the Journal reports. Chlamydia is particularly prevalent in women ages 15 to 19 and blacks, although sample studies have shown nearly 10% of all female Army recruits, 10% of female college freshmen and 14% of women in managed care plans are infected with chlamydia.Despite its prevalence, chlamydia is one of the least known STIs, which has compounded the difficulty of promoting screening efforts, the Journal reports. It causes few symptoms, and many people are unaware they were exposed to it. According to the Journal, many patients do not ask to be screened for the disease because the few symptoms it causes -- such as bleeding between periods, occasional vaginal discharge, pain during intercourse, pelvic pain in women, and burning upon urination in men -- are common to many conditions. While most screening efforts aim to identify active cases in younger women, there is a serious risk of infertility to older women who were exposed to the bacteria when they were younger, the Journal reports.According to the Journal, the chlamydia bacteria can move to a woman"s upper genital tract and set off pelvic inflammatory disease, which often leaves inflammation and scar tissue that obstructs a woman"s fallopian tubes and fertilization. PID is the most common cause of ectopic pregnancy and can cause endometriosis, a condition in which small portions of the uterine lining tissue grow outside the uterus, which can cause infertility and pain. Miklos Toth, a New York City-based ob-gyn, said, "It"s not the infection itself but the body"s response to get rid of the bacteria that causes scarring. And even if just some fragments of the bacteria remain, the immune system thinks an active infection is still present."According to the Journal, about 25% of women treated for chlamydia are re-infected within six months likely because of a partner who was not treated. CDC recommends that doctors prescribe a second course of antibiotics for partners of people with the infection. However, many doctors do not screen for or discuss chlamydia during office visits with their patients, especially pediatricians who may be uncomfortable discussing sexual activity with their younger patients, the Journal reports. Lynn Barclay, president of the American Social Health Association, said, "A lot of health care providers aren"t making the connection when they are dealing with adolescents. But to pretend that teenagers aren"t having sex is very dangerous."The Journal reports that the issue of how minors can pay for chlamydia testing can also create barriers. All 50 states allow minors to be tested and treated for STIs without parental consent. However, if a minor"s health insurance is provided by his or her parents, a lab fee listed on an explanation of benefits report for the testing could be considered a breach of confidentiality. Although some doctors suggest that minors pay the $40 to $90 cost for the test in cash, many refer younger patients to STI or family planning clinics that offer low- or no-cost testing. The Jour
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Opinion Piece Examines Abortion-Rights Opponents' Response To Connection Between Recession, Abortion
In response to recent news reports from Reuters, the Associated Press and other media outlets tying the recession to an increase in demand for abortion, the antiabortion-rights community is arguing that women are "choosing their own material comfort over the life of their unborn children" -- an interpretation that is "wrong on several accounts" -- Double X contributor Anna Murphy Paul writes in an opinion piece."No one wants her most intimate decisions to be driven by money," but, at the same time, "opting not to have a child you can"t afford to raise can be a realistic and responsible -- if painful -- choice, one often based on taking good care of the kids you already have" Murphy Paul says. She continues, "Nor is the intrusion of economic concerns on childbearing a phenomenon of this recession, or even the loosening of sexual mores over the past half-century; historically, financial hardship has been an ever-present motivation for ending a pregnancy."Murphy Paul cites the results of a 2005 Guttmacher Institute survey that found that nearly three-fourths of respondents said that the reason they decided to have an abortion was that they "could not afford a baby right now," which was the second-most common reason. The report found that the top reason for having an abortion was that children would interfere with women"s education, work or ability to care for dependents, all "concerns that are also largely economic in nature," Murphy Paul writes. She notes that at the time the study was published, "the Dow was still riding high, and the housing bubble seemed it would never pop." Murphy Paul adds that a 1987 Guttmacher survey on the same subject produced results "almost identical" to the 2005 survey.However, "to hear the pro-life activists tell it, women aren"t really struggling with difficult choices -- they just don"t want to give up the luxuries to which they"ve become accustomed," Murphy Paul writes. Abortion-rights opponents promote offers of counseling and no-cost infant supplies provided through "pregnancy re centers" to support women who choose not to have an abortion, but such centers often provide misleading information or offer little assistance beyond the first few months after birth, she says."Pro-life activists are surely right about one thing: It"s tremendously sad when a woman decides that she can"t bring into the world a child whom under better circumstances she would have welcomed," Murphy Paul continues. However, the "harsh rhetoric about selfishness and irresponsibility help far less than an acknowledgement of -- and lasting aid with -- the true costs of raising a child," she writes. According to Murphy Paul, in "the absence of such help, the most responsible act is to face economic reality head-on. For some women, that may mean abortion" (Murphy Paul, Double X, 5/15).
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RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment Delayed The Time To Relapse In Patients With Bipolar I Disorder
New data demonstrate that maintenance therapy with RISPERDAL(R) CONSTA(R) (risperidone) Long-Acting Treatment (RLAT) significantly delayed the time to relapse compared to placebo in patients with Bipolar I Disorder. Results of the study were presented this week at a major medical meeting.
Diagnostics

Quality Measures Improve Outcomes More Than Hospital Volume Alone

A new study by researchers at the University of California, San Francisco and Baystate Medical Center at Tufts University in Massachusetts concludes that patients facing coronary artery bypass surgery should, as a first priority, select a medical facility that has the highest adherence to quality standards. The research team sought to determine how volume among individual surgeons, volume differences between hospitals, and differences in quality of care might influence outcomes following coronary artery bypass surgery. According to the researchers, care from high-volume centers or surgeons has been associated with better outcomes post-operatively, but how volume and quality of care were related has not been well understood. "You could go to the busiest doctor, as many people do," said study author Andrew Auerbach, MD, MPH, associate clinical professor of medicine at UCSF and director of research for the Division of Hospital Medicine. "But how busy the surgeon is may not matter as much as his or her team"s adherence to quality measures." The study, "Shop for Quality or Volume? Volume, Quality, and Outcomes of Coronary Artery Bypass Surgery," is published in the May 19, 2009 edition of Annals of Internal Medicine. The study examined data on 81,289 patients cared for by 1,451 surgeons at 164 hospitals in the United States participating in Perspective, a voluntary, fee-supported database that measures quality and health care utilization. "Conventional wisdom suggests that patients in need of surgery should seek care from hospitals and surgeons that perform the procedure often - practice makes perfect," said study senior author Peter Lindenauer, MD, MSc, director of the Center for Quality of Care Research at Baystate Medical Center and associate professor of medicine at Tufts University School of Medicine. Very little is known about what makes high volume centers or surgeons more successful, the researchers noted, and the study team sought to investigate whether some of the success factors of high volume centers or surgeons could be replicable at low volume centers. If so, then perhaps some of the risks associated with going to a low volume center could be mitigated, they said. Findings showed patients have better outcomes when patient care teams strictly follow a routine of individual quality measures, independent of the volume of procedures performed. Those surgeons and hospitals that performed best on meeting every one of six quality measures had the best outcomes, regardless of their patient volume, the researchers found. The research also showed that meeting quality measures seems to have an "all or nothing" effect. If a patient care team misses individual quality measures, positive post-operative outcomes decline precipitously. Study results suggested a strong association between the number of quality measures missed and death rates regardless of annual hospital volume for coronary artery bypass surgery, with mortality rates similar across all levels of hospital volume if no quality measures are missed. The six quality measures were whether antimicrobials were used to prevent surgical site infection on the operative day, whether the antimicrobial was appropriate, whether serial compression devices were used to prevent venous thromboembolism on the operative day, and whether aspirin, beta-blockers, or statin lipid-lowering drugs were administered in the first two days after surgery. The research team found that what made the biggest difference in mortality was whether any of the quality measures were missed. "It doesn"t help if you got your aspirin but you didn"t get your beta-blockers," said Auerbach. "You have to have everything on the list, or else a good explanation for why you did not." Auerbach noted that the researchers assumed doctors in the study were administering medicines smartly; for example, they would not give aspirin to a patient at risk for hemorrhage. "We are saying in essence, it does not matter if you get an "A" in English, and an "A" in science, and an "A" in history, but a "B" in math. You need to have an "A" in everything," he added. The study showed that patients cared for at low volume hospitals whose aggregate quality scores were high did as well as patients at high volume centers. "Volume alone did not make as much difference as we thought," said Auerbach. The implication for payers is that they may want to think in terms of two different domains, volume and quality, to determine the return on their investment in deciding to cover the procedure in one medical center rather than another, according to the research team. The message for low-volume surgeons is that they can have the same high quality of care with the same level of good outcomes if they have systems in place to ensure that all quality measures are adhered to every single time, said the researchers. Auerbach said that this success depends on the surgeon"s team, that someone on the team is coordinating care to ensure it is reliable and consistent. "Our results suggest that patients should make use of publicly available quality measures and are likely to benefit from seeking care at hospitals with higher quality scores," said Lindenauer. Study co-authors are Joan Hilton, ScD, UCSF Department of Epidemiology and Biostatistics; Judith Maselli, MSPH, UCSF Department of Medicine; and Penelope Pekow, PhD, and Michael Rothberg, MD, MPH, Baystate Medical Center, Center for Quality of Care Research. The study was funded by a grant from the California HealthCare Foundation. Kirsten Michener University of California - San Francisco


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