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Recent Survey Suggests Complications With Permanent Fillers - 1 In 4 UK Surgeons Have Seen Patients With Complications
A new survey completed by the British Association of Aesthetic Plastic Surgery (BAAPS) suggests that patients may experience higher complication rates with permanent cosmetic fillers than with other types of cosmetic injections. The survey reveals 38.5% of surgeons saw 1-3 patients over the past year experiencing complications with permanent facial fillers, and 23% of surgeons saw 1-3 patients in the past year with complications so severe surgery was needed to treat those complications. "Permanent fillers present challenges, particularly for inexperienced injectors," says Coalition leader Julius Few, MD, a plastic surgeon practicing in Chicago, IL. "In addition to potential complications that may develop years after injection, the challenge of a permanent, synthetic filler is the anticipation of aging changes and the need for outcomes that will not look unnatural over time. To date, fat continues to be the option closest to a permanent filler with a proven safety record."
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A.P. Pharma Announces FDA Acceptance Of APF530 New Drug Application For Chemotherapy-Induced Nausea And Vomiting
A.P. Pharma, Inc. (Nasdaq:APPA), a specialty pharmaceutical company, announced that the U.S. Food and Drug Administration (FDA) has accepted for review the New Drug Application (NDA) for APF530 for the potential treatment of chemotherapy-induced nausea and vomiting (CINV). APF530 is a long-acting formulation of granisetron that utilizes the Company"s proprietary Biochronomer™ drug delivery system. Based on the Prescription Drug User Fee Act (PDUFA), the FDA has issued an action date of March 18, 2010.
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Oncologic Drugs Advisory Committee Meeting Set By FDA
Medical Industry E-Mail News Service™ -- July 07 2009 -- The US Food & Drug Administration (FDA) has announced that its Oncologic Drugs Advisory Committee will meet on July 15 2009, in Gaithersburg MD, to discuss (1) new drug application (NDA) 022-447, proposed trade name Yondelis (trabectedin) powder, for concentrate for solution for intravenous infusion, Centocor Ortho Biotech Products, L.P., proposed indication in combination with Doxcil (doxorubicin HCl liposome injection), for treating patients with relapsed ovarian cancer; and (2) supplemental new drug application (sNDA) 050-718/S-039, Doxil (doxorubicin HCl liposome injection), for intravenous infusion, Centocor Ortho Biotech Products, L.P., proposed indication in combination with docetaxel for treating patients with locally advanced or metasatic breast cancer who have received prior anthracycline treatment. There is no charge to attend.
Endocrinology

Realistic Perception Of Risk Is Key To Motivate People To Take Protective Action Against New Infectious Diseases

With the current outbreak of swine flu, and in the absence of a vaccine or treatment at present, the only way to contain the virus is to get people around the world to take precautionary measures. In a special editorial1 in the latest issue of Springer"s International Journal of Behavioral Medicine, Johannes Brug, Arja Aro, and Jan Hendrik Richardus show that there are three key parameters that convince people to take precautions. Firstly, they need to be aware of the risk to them. Secondly, they need to believe that effective protective actions are available and have confidence in them. Lastly, communications about risk need to be carefully managed so that they express the actual risk accurately to prevent mass scares. The authors review the importance of risk perception and show that for people to voluntarily take precautionary actions, it is essential that they are aware of and understand the risk. Indeed, risk perception is a key feature of many health behavior theories. On the one hand, unrealistic optimism about health risks is often observed in relation to familiar risks and can result in a false sense of security and lack of precautions. On the other hand, pessimism is more likely for new, unfamiliar risks that are perceived to be uncontrollable and may lead to unnecessary mass scares. As a consequence, implementation of precautionary measures requires effective risk communication that leads to realistic perceptions of risk, as well as knowledge and skills to promote precautionary practices. The authors argue that scientific knowledge in the area of infectious disease control is limited. Looking at how risk is communicated, they show that, in the early stages of a possible pandemic, risk perceptions and people"s confidence in recommended protective actions depend on effective communications. In the authors" view: "Risk communication messages that are not comprehended by the public at risk, or communication of conflicting risk messages will result in lack of precautionary actions, as will communications from a non-trustworthy . However, risk communication messages are sometimes very quickly adopted by the media, possibly leading to an "amplification" of risk information that may lead to unnecessary mass scares and unnecessary or ineffective precautionary action." This editorial is published in the latest issue of the International Journal of Behavioral Medicine, dedicated to lessons learned from both the SARS and avian flu outbreaks. Overall, the studies in this issue show that people across Europe and East Asia do regard recently emerging infectious diseases as serious potential health threats, based on information received from various s, with clear differences between countries and regions. The International Journal of Behavioral Medicine is the official journal of the International Society of Behavioral Medicine. Reference 1. Brug J, Aro AR, Richardus JH.(2009). Risk Perceptions and Behaviour: Towards Pandemic Control of Emerging Infectious Diseases. International Journal of Behavioral Medicine. DOI 10.1007/s12529-008-9000-X Renate Bayaz Springer


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