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New Mechanism Fundamental To The Spread Of Invasive Yeast Infections Identified
A group of researchers led by Carnegie Mellon University Biological Sciences Professor Aaron Mitchell has identified a novel regulatory gene network that plays an important role in the spread of common, and sometimes deadly, yeast infections. The findings, which establish the role of Zap1 protein in the activation of genes that regulate the synthesis of biofilm matrix, will be published in the June 16, 2009, issue of PLoS Biology, a peer-reviewed open-access journal from the Public Library of Science.
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HIV/AIDS Groups Demonstrate At Capitol Rotunda, Call For Action On Domestic, Global Epidemics
Twenty-six people representing a coalition of five HIV/AIDS groups from Washington, D.C., Philadelphia and New York were arrested on Thursday for unlawfully demonstrating in the Capitol rotunda, the AP/Washington Post reports (7/9). According to Politico, the protestors were demanding "congressional action on three AIDS priorities: the end of the federal ban on syringe exchange, increased housing funding for [people living with AIDS] and significant increases in U.S. international AIDS contributions" (McGrane, 7/9). The group contends that the Obama "administration"s budget proposal "essentially flatlines global AIDS funding,"" CNN.com reports. In a statement, Omolola Adele-Oso of DC Fights Back, said, "HIV is not in recession. So why are we bailing out the bankers with $9 trillion, but breaking promises to fund life-saving AIDS programs in the U.S. and around the world at a fraction of that cost?" (7/9).
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Award For Pioneering Stem Cell Research To Mend Broken Bones
Funding from the Biotechnology and Biological Sciences Research Council (BBSRC) could lead to the development of new and better treatments for broken bones and other orthopaedic problems associated with ageing.
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SNM's Clinical Trials Network Gains Added Support From Industry Leader

The SNM Clinical Trials Network, an initiative designed to address the need for streamlined drug discovery through the integration of imaging biomarkers into multi-center clinical trials, recently added Genentech, Inc. as a supporter. SNM, the world"s largest medical and scientific society for molecular imaging professionals, inaugurated the Clinical Trials Network in late 2008 to facilitate more cost-effective drug development through the integration and standardization of imaging biomarkers into Phase 1, 2, 3 and 4 therapeutic clinical trials. As part of this initiative, the society continues to bring together pharmaceutical developers, the imaging community, biomarker manufacturers and regulatory agencies to address critical needs for incorporating imaging biomarkers into multi-center trials. A formal introduction to the Clinical Trials Network was provided at a two-day workshop in Clearwater Beach, Fla. in February 2009 and additional educational sessions about the network are planned for June during SNM"s 56th Annual Meeting in Toronto, Canada. "We are gratified to have Genentech - a pioneer in the field of developing targeted therapeutics - join us in this important endeavor, which we hope will broaden the scope and effectiveness of today"s medical practice and lead to improved patient care in the near future," said Peter S. Conti, M.D., Ph.D., co-chair of the SNM Clinical Trials Network and professor of radiology, pharmacy and biomedical engineering at the University of Southern California. "We are pleased that such an innovative corporate leader supports our mission of advancing molecular imaging and therapy." The use of imaging in clinical trials can help pharmaceutical developers determine earlier in the development process whether a new product is clinically promising by allowing physicians to see and assess whether it is working as intended for a patient, explained Dr. Conti. "Molecular imaging is an essential component of such studies since it accelerates the development of promising compounds and eliminates those without apparent patient benefit earlier in the development cycle," he added. "We hope that Genentech"s collaboration with SNM will help improve patient treatment worldwide." Amy Shaw Society of Nuclear Medicine


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