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Amyloid Aggregations And Tau Pathology Reflected By Cortical Thickness In The Default Network Of MCI And AD
Alzheimer"s disease patients show a relentless decline in memory over the course of the disease, which is accompanied by both brain atrophy and by characteristic deposits in the brain tissue called amyloid plaques and neurofibrillary tangles. Researchers from the Chinese Academy of Sciences studied a large database, collected in the US, of patients with Alzheimer"s or memory complaints who had MRI scans and had spinal taps to collect cerebrospinal fluid, which is in the brain and spinal chord. By examining the CFS they could measure the amounts of the substances that make p plaques and tangles, and related this to brain atrophy. They found that the amount of plaque and tangle-producing chemicals in the cerebrospinal fluid correlated with brain tissue loss in selective regions of the brain which are typically affected in Alzheimer"s disease. The brains in these regions had thinned out suggesting that brain cells had died. These regions are important for memory and are typically active when the brain is at rest. Using these techniques may ultimately help identify early markers of disease in Alzheimer"s, potentially indicating who is likely to develop Alzheimer"s before memory loss is critical.
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Training Program To Prevent Groundwater Poisoning In India
A team of scientists at Queen"s University has been chosen to lead a top research and training programme to prevent groundwater poisoning in India.
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Global Health Programmes Improve Specific Health Outcomes But Can Constrain Health Systems Of Poor Countries
The emergence of global health initiatives (GHIs), eg, The Global Fund and PEPFAR, has resulted in a striking expansion of key health interventions in recent years, from which millions have benefited. There is also evidence, however, that such initiatives can constrain the health systems of poor countries and that many opportunities to improve efficiency, equity, value for money and outcomes in global public health are still being missed. The health systems strengthening agenda needs more investment, and to be infused with the same sense of ambition and speed that has characterised GHIs. This is one of five key recommendations in a new multi-partner report published in a Health Policy paper in this week"s edition of The Lancet.
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Stem Cell Lawyer Says Let Women Be Paid For Egg Donations

Last week, New York became the first state in America to allow scientists to pay women for donating their eggs for use in stem cell research, triggering further ethical debate. Professor Loane Skene of the Faculty of Law at the University of Melbourne and Deputy Chair of the high-profile Lockhart Committee on Human Cloning and Embryo Research (2005) says women should be paid for the invasive procedure. "This is not lawful in Australia but if embryo research leads to new cures, this ban may be reconsidered," Professor Skene says. "Given the invasiveness of extracting eggs for donation to medical research, it seems reasonable for women to receive some financial compensation, " she says. Professor Skene says that although other organ donation is free in Australia, typically organs are donated to a family member or friend. "It is unusual that organ donation is done for a complete stranger. For the effort of undergoing surgery to help medical research, I think it is appropriate for women to be remunerated." "We would be living in a nanny state if we said women may be exploited for being paid for the procedure," she says. "People undertake risky jobs every day. This is no different to a consenting adult who knows the risks of surgery making an informed decision." "When there is a breakthrough in stem cell research we will find this will be the impetus for new laws. It will reflect the push from scientists and government to be able to further investigate revolutionary treatments in this emerging field." "Stem cell research is going to be a very competitive field. It is still very early days." Professor Skene will outline social, ethical and regulatory issues raised by developments in stem cell research and explore legal responses in Australia and globally, at the 4th David Danks Oration at the University of Melbourne on Tuesday 7 July. WHAT Public Lecture "Recent developments in stem cell research: social, ethical and legal issues for the future" WHEN 6:00 - 7:00pm, Tuesday 7 July 2009 WHERE Sunderland Lecture Theatre, ground floor, Medical Building, corner of Grattan Street and Royal Parade, The University of Melbourne, Parkville (Melways reference: Map 2B C7) University of Melbourne


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